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NFL Week 11: Chiefs and Chargers Headline Monday Night Football

Week 10 was a crazy week for the NFL betting odds. A number of underdogs managed high-profile upsets, including the Seattle Seahawks (+4) who look down the formerly undefeated San Francisco 49ers. Now in Week 11, we can expect several teams to come out with a vengeance as they look to get back in the win column. None will be more motivated than the Kansas City Chiefs, who lost in Patrick Mahomes’ first game back from injury. They’ll be up against an unpredictable Chargers squad this week, so read on as we break down this and rest of the top-10 NFL betting matchups for Week 11.

NFL Week 11 Best Odds and Matchups

Kansas City Chiefs at Los Angeles Chargers (Monday, 8:15 PM ET)

The Chiefs (6-4 SU, 5-5 ATS) will be on Monday Night Football for the first time this season, and Patrick Mahomes will look to lead his stumbling Chiefs to victory against the Chargers (4-6 SU, 3-5-2 ATS). Mahomes’ mobility was visibly limited in his first game back since suffering a knee injury in Week 7. Despite that, the visiting Chiefs are still favourites against the Chargers, laying 4 points on the NFL lines, with a week-high total of 52.

Pittsburgh Steelers at Cleveland Browns (Thursday, 8:20 PM ET)

Both the Browns (3-6 SU, 2-6-1 ATS) and Steelers (5-4 SU, 6-3 ATS) are coming off of victories in games where they were underdogs. Despite the Steelers’ better record, they’re 2.5-point road dogs with a 40.5-point total. It’ll be a toss-up for these two defensive teams that average 40.4 points per game between both of them.

Jacksonville Jaguars at Indianapolis Colts (Sunday, 1 PM ET)

At long last, the Jacksonville Jaguars (4-5 SU, 5-4 ATS) will get their prized offseason signing Nick Foles back on the field on Sunday. Coming off of a Bye, the Jags still have a chance in the AFC South. It’s perfect timing for Foles’ return, as they face a team that they’re chasing in the standing: the Colts (5-4 SU, 4-4-1 ATS). The odds on NFL Sunday haven’t been posted for this one yet, so stay tuned.

Dallas Cowboys at Detroit Lions (Sunday, 1 PM ET)

A game typically reserved for Thanksgiving will happen this Sunday when the Cowboys (5-4 SU and ATS) visit the Lions (3-5-1 SU, 4-5 ATS). Dallas may not have to face Matt Stafford in this one, as he’s currently battling a back injury. Once we receive confirmation of Stafford’s status, the NFL odds will be posted.

Houston Texans at Baltimore Ravens (Sunday, 1 PM ET)

Two of the top offenses will meet in Baltimore as Deshaun Watson and the Texans (6-3 SU, 5-4 ATS) visit the Ravens (7-2 SU, 4-5 ATS). We expect this one to be a high-scoring affair, as reflected by the 50-point total; the Ravens are laying 4.5 points on the spread.

New Orleans Saints at Tampa Bay Buccaneers (Sunday, 1 PM ET)

Perhaps the biggest upset in Week 10 was the Saints’ 26-9 loss to the Atlanta Falcons. Drew Brees was held to just 287 passing yards and zero touchdowns, and the Saints’ offense looked lethargic throughout. They’ll have a chance to rebound against a last-place Buc’s defense that surrenders 31 points per game. New Orleans are 5.5-point favourites on the road.

Denver Broncos at Minnesota Vikings (Sunday, 1 PM ET)

The Vikes are on the Packers’ heels, moving to 7-3 SU, 6-4 ATS in the race for the NFC North. Their matchup versus the Broncos will likely come down to whether Minnesota’s fifth-ranked D can hold down Denver’s fifth-last offense enough to beat the lofty 10.5-point spread.

Arizona Cardinals at San Francisco 49ers (Sunday, 4:05 PM ET)

One week removed from their first loss of the season, San Francisco (8-1 SU, 5-4 ATS) will be up against a team that’s been shredding the NFL lines so far this season. The Arizona Cardinals (3-6-1 SU, 7-3 ATS) have been very friendly to those who bet on the NFL, so it’s worth considering the underdog Cards (+11.5) as a potential upset against the 49ers.

New England Patriots at Philadelphia Eagles (Sunday, 4:25 PM ET)

The New England Patriots (8-1 SU, 6-3 ATS) are fresh off their Bye, but also coming off of their first loss of the season. You can bet they’ll be ready to continue their run to Super Bowl LIV with a Week 11 victory against the Eagles (5-4 SU, 4-5 ATS). Despite the lopsided records, New England is giving up just four points with a total of 44.5.

Chicago Bears at Los Angeles Rams (Sunday, 8:20 PM ET)

The LA Rams are a tough nut to crack this year. At 5-4 SU, 6-3 ATS, they have shown consistency to their bettors. After losing to the Steelers last week, they’ll look to rebound when they host the Bears (4-5 SU, 3-6 ATS) on Sunday. The Rams are 7-point home favourites in a game with significant implications for both clubs.